Clinical Trials: Rheumatology

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25 results

This is a Phase 2, multicentre, multinational, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of two intravenous (IV) treatment regimens of anifrolumab versus placebo while taking standard of care (SOC) treatment with mycophenolate mofetil (MMF) and corticosteroids in adult subjects with active proliferative lupus nephritis (LN).

Rheumatology | 865 Northern Blvd | Great Neck, NY 11021


The purpose of this study is to determine if hydroxychloroquine (HCQ) is safe and effective for the prevention of future onset of rheumatoid arthritis (RA) in individuals who have elevations of an autoantibody, anti-cyclic citrullinated peptide (anti-CCP).

Rheumatology | 865 Northern Blvd | Great Neck, NY 11021


The purpose of this multi-center pilot study is to determine if the drug tocilizumab (Actemra) is effective in the treatment of patients with refractory adult polymyositis (PM) and dermatomyositis (DM).

Rheumatology | 865 Northern Blvd | Great Neck, NY 11021


The goal of the trial is to evaluate the efficacy and safety of belimumab as a maintenance therapy in adults with refractory Idiopathic inflammatory myositis (IIM) as compared with standard of care...

Rheumatology | 865 Northern Blvd | Great Neck, NY 11021


The purpose of the study is to examine the cells and proteins in the tissue from the inflamed joints of patients with rheumatoid arthritis. Study samples will be obtained via a minimally invasive ultrasound guided synovial tissue biopsy on the knee and wrist joints...

Rheumatology | 865 Northern Blvd | Great Neck, NY 11021


This Phase II study will compare the efficacy and safety of obinutuzumab plus mycophenolate (MMF) with placebo plus MMF in Class III and IV patients with proliferative Lupus Nephritis (LN).

Rheumatology | 865 Northern Blvd | Great Neck, NY 11021


To demonstrate that the efficacy of secukinumab 300 mg at Week 16 is superior to placebo in adult patients with active PsA based on the proportion of patients achieving an American College of Rheumatology 20 (ACR20) response.

Rheumatology | 865 Northern Blvd | Great Neck, NY 11021


SLE Sample Acquisition in patients who are 18 or older with a diagnoses of systemic lupus erythematosus (SLE) with active disease.

Rheumatology | 865 Northern Blvd | Great Neck, NY 11021


In this study, participants receive standard therapy (induction and maintenance) for lupus nephritis in addition to receiving either placebo (no active medicine) or belimumab...

Rheumatology | 865 Northern Blvd | Great Neck, NY 11021


This study evaluates the impact of 13 bi-weekly intravenous infusions of RSLV-132 on cutaneous manifestations in subjects with systemic lupus erythematosus.

Rheumatology | 865 Northern Blvd | Great Neck, NY 11021


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