Clinical Trials: Heart

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32 results

The objective of the study is to compare the use of Ticagrelor (platelet aggregation inhibitor) alone vs Ticagrelor and aspirin together in reducing clinically significant bleeding and in reducing ischemic adverse events among high risk patients who have had PCI with at least one drug eluting stent.

Multiple Locations


The primary purpose of this study is to determine whether treatment with the Cobra PzF stent with 14 day Dual Anti-Platelet Therapy (DAPT) has a better safety profile compared to standard FDA approved Drug Eluting Stent plus 6-Month Dual Anti-Platelet Therapy in patients undergoing coronary intervention who also require oral anticoagulation.

Multiple Locations


The objective of this study is to assess whether a Rivaroxaban based anticoagulation therapy, after a successful TAVR, is superior in reducing death or first thromboembolic events, compared to a Antiplatelet based therapy.

North Shore University Hospital | 300 Community Dr | Manhasset, NY 11030


The purpose of this study is to study the efficacy and safety of Edoxoban versus Vitamin K antagonist when used concomitantly with anti-platelet therapy in patients with non-valvular AF following PCI with stent placement.

Multiple Locations


The objective of the study is to assess the use of HeartMate PHP System which is a temporary (<6 hours) ventricular assist device indicated for use during high risk PCI(percutaneous coronary interventions performed in elective or urgent, hemodynamically stable patients with severe coronary artery disease and depressed Left Ventricular ejection fraction(<35%).

Multiple Locations


The objective of this study is to evaluate the effectiveness of MicroVention Carotid Stent System used in conjunction with the Nanoparasol embolic protection system for the treatment of carotid artery stenosis in patients with elevated risk for adverse events following carotid endarterectomy...

Lenox Hill Hospital | 100 E 77th St | New York, NY 10075


The main objective of this study is to determine the 18-month incidence of inappropriate shocks in subjects implanted with the EMBLEM Subcutaneous Implantable Defibrillator (S-ICD) for primary prevention of sudden cardiac death...

Multiple Locations


The purpose of the ISCHEMIA trial is to determine the best management strategy for higher-risk patients with stable ischemic heart disease. This is a multicenter randomized controlled trial with a target enrollment of ~8000 patients with at least moderate ischemia on stress imaging...

North Shore University Hospital | 300 Community Dr | Manhasset, NY 11030


This research study is investigating a medical device called the ZOLL Short-term use Wearable Defibrillator (“SWD 1000”).  A defibrillator is a device used to control an abnormal heart beat by applying an electric current, also known as "shocking", to the chest wall or heart...

Staten Island University Hospital North Campus | 475 Seaview Ave | Staten Island, NY 10305


To evaluate the safety and effectiveness of the Lotus™ Valve System for transcatheter aortic valve replacement (TAVR) in symptomatic subjects with calcific, severe native aortic stenosis who are considered at extreme or high risk for surgical valve replacement 

North Shore University Hospital | 300 Community Dr | Manhasset, NY 11030


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