Skip to main content
head shot of Horacio L. Ril
Pancreas Disease Center Cellular Transplant, Tissue Engineering and Regenerative Medicine

Professor of Surgery and Medicine
Donald and Barbara Zucker School of Medicine at Hofstra/Northwell

Horacio L. Rilo, M.D. is a pioneer in the field of cell transplantation. He has built several programs that are among the most active and successful in the world, and possesses one of the largest world experiences in clinical islet transplantation. He has performed more than 350 clinical islet isolations for autologous and allogeneic islet patients, with more than 200 isolations since 2002 alone.  

Dr. Rilo has 26 years of experience and clinical expertise in the field of cell transplant/cell therapy, including writing and managing clinical trials as principal investigator and in developing and directing clinical programs under FDA Good Manufacturing/Tissue Practice guidelines. He successfully developed clinical and research programs at the Universities of Chicago, Cincinnati, Tucson and New York and has consulted on the development of programs in Charleston and Georgetown. 

He has more than 20 years of clinical experience in the isolation and transplantation of cells, including allogeneic islets for type 1 diabetes and hepatocytes for patients suffering from liver failure and metabolic disorders. He has also performed cadaveric bone marrow transplantation for induction of immunological tolerance in solid organ and dendritic cells for the treatment of cancer. He has extensive experience and expertise in relevant translational models of in vitro and in vivo studies.

He is currently a Professor of Surgery at the Zucker School of Medicine and Director for the Pancreas Disease Center. The Center is multidisciplinary and draws patients from across New York and Northwell’s 21 hospitals and 300 outpatient clinics.

Prior to coming to New York, Dr. Rilo directed the University of Arizona Institute for Cell Transplantation and the Comprehensive Center for Chronic Pancreatitis. He was a tenured professor with appointments in Biomedical Engineering, Mechanical and Aerospace Engineering, Physiology, Cell Biology, Immunology, and the Bio 5 Institute for Collaborative BioResearch. He is on faculty at the Southern Arizona Limb Alliance and a member of VIPER (Venom Immunochemistry, Pharmacology and Emergency Response) Institute.