John Locke's Law of Unintended Consequences dates back to the 1600s. Often cited, the law says that actions always have effects that are unanticipated or unintended.
Locke's law couldn't be truer for childhood cancer survivors today.
Survivorship is a significant milestone that has accelerated since the 1970s, when the cure rate was 50-60 percent. Today, four out of five children diagnosed with cancer will be cured.
This is good news for extending life away from the disease, but treatments - predominantly chemotherapy, radiation and surgery- have unintentionally caused a multitude of issues as survivors age.
Studies show that over two-thirds of childhood cancer survivors are living with chronic conditions and even life-threatening illness. As of 2010, there were 380,000 survivors living in the US, and projections call for a half-million survivors by 2020. The math adds up to a public health concern.