Mitchell Edward Levine, MD

Mitchell Edward Levine, MD

Director, Spine Surgery, Department of Neurosurgery
Lenox Hill Hospital

Director, Spine Center
Institute for Neurology and Neurosurgery

Assistant Professor, Neurosurgery
Donald and Barbara Zucker School of Medicine at Hofstra/Northwell

Mitchell E. Levine, MD joined the North Shore-LIJ Health System (now Northwell Health) in 2005 after over 20 years of practice and is currently the Director of Spine Surgery within the Department of Neurosurgery at Lenox Hill Hospital. He is also Assistant Professor of Neurosurgery at the Zucker School of Medicine. During his career Dr. Levine has concentrated on complex and minimally invasive spine surgery, facial pain, trigeminal neuralgia, pain modulation procedures and radiosurgery.

Dr. Levine received his medical degree from Mount Sinai School of Medicine and continued his training there in neurosurgery. Under the pioneering microneurosurgeon Dr. Leonard Malis, Dr. Levine was appointed Director of Spinal Neurosurgery at Mount Sinai and then the Director of Neurosurgery at the New York Hospital Queens before joining Northwell. As a resident, he won the prestigious New York Neurosurgical Society Resident Award. Dr. Levine was also a National Institutes of Health neurotraumatolgy fellow at the Medical College of Virginia.

Among his accomplishments, Dr. Levine performed the first “early” aneurysm surgery at Mount Sinai and pioneered the use of temporary clip occlusion in complex aneurysm cases. More recently, he investigated the use of a novel radiotherapy treatment for malignant brain tumors and has presented his work on the radiosurgical treatment of multiple brain metastasis. In addition, Dr. Levine’s clinical and research interests include neuromodulation and the interface of technology and biology, as well as the understanding of the molecular mechanisms of intervetebral disc degeneration and repair. Dr. Levine is one of the few clinically expert spine surgeons to be actively involved in laboratory research and has widely published with Dr. Chahine. 


BS with Honors State University of New York at Stony Brook  1972
MD Mount Sinai School of Medicine, New York  1977
Internship  Mount Sinai Hospital, New York 1977-8
Mount Sinai Hospital, New York   1978-82
Fellow- NIH
Medical College of Virginia, Richmond, VA 1980
Chief Resident 
Mount Sinai Hospital, New York      1982-83 



  • Resident Award, New York Neurosurgical Society, 1981
  • Listing in New York Magazine “Best Doctors”
  • Newsday Long Island “Top Doctors on Long Island”
  • Castle Connoly Guide

Faculty Appointments

Assistant Professor, Neurosurgery Hofstra School of Medicine, 2010

Hospital Appointments

  • Director, Spine Surgery, Department of Neurosurgery, Lenox Hill Hospital, 2014- Present
  • Director, Spine Center, Institute for Neurology and Neurosurgery, Northwell Health, 2006- Present
  • Director, Division of Neurosurgery, New York Hospital Queens, 1986- 2006
  • Director, Division of Neurosurgery, Peninsula Hospital, 1983- Present
  • Director, Division of Neurosurgery, St. John’s Episcopal Hospital, 1983-Present
  • Attending Neurosurgeon, Mount Sinai Hospital, New York, 1983-1996


New York State

Board Certification

American Board of Neurological Surgeons

Clinical Interests

  • Minimally Invasive Spine Surgery
  • Cerebrovascular Surgery
  • Radiosurgery
  • Brain Tumor Surgery

Research Interests

  • Biological Mechanics
  • Tissue engineering
  • Disc Nucleus Prosthesis


Weber, K.T., Alipui, D.O., Sison, C., Bloom, O., Quraishi, S., Overby, C., Levine, M.E., Chahine, N.O.: "Serum Levels of the Pro-inflammatory Cytokine IL-6 Vary Based on Diagnoses in Individuals with Lumbar Intervertebral Disc Diseases" Arthritis Research & Therapy, ARRT-D-15-00054R1 (Accepted for Publication, 2015)

Drapkin,A.J., Levine, M.E., Yang, W..L.: “Ventriculo-Subgaleal Shunt: Evaluation by Computed Tomography,” Acta. Neurochir, 55: 107-115, 1980

Levine, M.E., Carlton, S.M., Becker, D.P., et al: “The Effect of Changing Arterial CO2 Tension on the Firing Rate of Neurons in the Region of the Locus Coeruleus in the Cat,” J. Cereb. Blood Flow Metab, 1: 8297-298, 1981

Levine, M.E., Carlton, S.M., Becker, D.P., et al: “CO2 Sensitive Neurons in the Cat Pontine Reticular Formation,” Soc. Neurosci. Abs., 7:941, 1981

Hollin, S.A., Levine , M.E., Sukoff, M. H., et al: “Neurological Complications of Hyperbaric Oxygen Therapy,” in Silverstein, A., (Ed), Neurological Complications of Therapy, pp. 425-463 Futura  1982

Levine, M.E., Carlton, S.M., Becker, D.P., et al: “Encoding of Arterial CO2 Tensions by Neurons in the Region of the Locus Coeruleus in the Cat,” in Heistad, D.D. and Marcus, M.L.(Eds) , Cerebral Blood Flow  pp. 503-508, Elsevier, New York 1982

Levine, M.E., DeWitt, D.S., Becker, D.P., et al: “A New Technique for the Measurement of Cerebral Blood Volume Using 3mu Micospheres,” in Go, K. (Ed), Brain Edema, Elsevier, New York, 1984

Levine, M.E., Spiegelman, M.K., Zapulla, R.A.: “Anatomical Studies of Blood Brain Barrier Disruption Following Intracarotid Bile Salt Infusion,” in Ishii, S. and Nagal, H. (Eds), Intracranial Pressure V, Springer-Verlag, 1983

Rosenblum, B.R., Overby, M. C., Levine, M.E., et al, “Monostotic Fibrous Dysplasia of the Thoracic Spine, “   Spine, 12: (9), 939-942, 1987

Grabel, J.C., Levine, M.E., Hollis, P.H., et al: “Moyamoya-like Disease Associated with Lenticulostriate Region Aneurysms,” J. Neurosurgery, 70:802-803, 1989

Dickerman R.D., Overby C., Eisenberg, M.E., Hollis, P, Levine, M.E., “The Steroid  Responsive Hiccup Reflex Arc , Competitive binding to the Corticosteroid Receptor?”, Neuroendocrinology Letters, 24 : 59-60 , 2003

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