The division of neuropathology in the Department of Pathology at Northwell Health provides diagnosis and consultations on disorders of the brain and central nervous system. The division provides the tissue diagnosis for all specimens that come from our hospitals in conjunction with the Brain Tumor Institute and Cushing Neuroscience Institutes.
Neuropathology has been established in the Department of Pathology for over 30 years. Our neuropathologists provide service to the Childhood Brain and Spinal Cord Tumor Center in the Steven and Alexandra Cohen Children's Medical Center of New York (CCMC) in New Hyde Park. The Childhood Brain and Spinal Cord Tumor Center at CCMC is committed to providing comprehensive, innovative, state-of-the-art care for children diagnosed with tumors of the nervous system. Their multidisciplinary team is dedicated to treating the broad spectrum of benign, malignant, primary and metastatic tumors in young patients whose bodies and brains are still developing.
The Division of Neuropathology provides support to the Movement Disorders Institute, which is dedicated to pushing the frontiers of these neurological conditions through clinical treatment and research. Movement disorders are neurological conditions that can result in spasticity, rigidity, tremor, involuntary movement and ataxia. We provide muscle biopsy reporting with the help of State University of New York, Stony Brook campus. We have a dedicated electron microscopy department at North Shore University Hospital which examines all of our muscle biopsies for disease.
We have the capability to provide the latest tests, like 1p/19q co-deletion, IDH1 Mutation, BRAF mutation, and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation assays for gliomas, and molecular subclassification for medulloblastomas. These assays are not provided in every hospital, and this is great asset to provide molecular pathology testing for the patients who get treated at Northwell Health.
We consult with referring physicians on issues related to patient care and can also offer family members information about the causes or the genetic components of a disease.
Mansoor M. Nasim, MD
- Co-Chief - Neuropathology of Pathology and Laboratory Medicine, North Shore University Hospital
- Assistant Professor, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
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The consultation service aims to respond to requests within 24 hours of the receipt of material. Our neuropathologists personally provide a verbal report to the requesting physician and send the final report by fax. Written reports on post-mortem evaluations are generally provided within two to four weeks. All neuropathologists are available for phone consultations. Pathology material can be returned, if requested. Autopsy specimens are returned promptly upon request, and surgical specimens will be returned promptly after the evaluation and report are completed.
Our laboratory is fully equipped to perform the special diagnostic tests needed to study tumor and degenerative diseases of the brain, and our nueropathologists have vast experience doing the special stains required for these studies. We are skilled in interpreting stereotactic needle biopsies of brain lesions and can perform in-situ hybridization, immunohistochemistry, light microscopy, immunofluorescence and electron microscopy, as necessary.
We have the capability to provide the latest tests, like 1p/19q co-deletion, IDH1 Mutation, BRAF mutation, and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation assays for gliomas, Next Generation Sequencing (on request) and molecular subclassification for medulloblastomas. These assays are not provided in every hospital, and this is great asset to provide molecular pathology testing for the patients who get treated at Northwell Health