Progressive supranuclear palsy

Progressive supranuclear palsy (PSP) is a neurodegenerative disease, and is one of the many Parkinson plus syndromes, meaning it presents with symptoms similar to Parkinson’s disease, but has a different cause. PSP develops in people who are middle-aged or elderly and progressively worsens. It is not usually genetic in nature.

Physical symptoms include a loss of balance, especially when walking, and problems with eye movement, such as double-vision or the inability to focus. Patients may also experience a contraction of facial muscles, sensitivity to light, problems swallowing and speaking, and sleep disorders. 

Cognitive symptoms resulting from the deterioration of frontal lobe function may also be present, such as slowed reasoning and the inability to retrieve information. Behavioral symptoms include depression, withdrawal, a lack of empathy, and uncontrolled impulses. Although there are no effective treatments for progressive supranuclear palsy, medication and physical therapy may relieve some of its symptoms.

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