Gastrointestinal pathology

Gastrointestinal pathology

Overview

The Gastrointestinal Pathology service offers broad experience in adult gastrointestinal and pancreaticobiliary disease, including fine needle aspirations and biopsies, endoscopic biopsies and surgical resection specimens. Our pathology group provides the highest quality GI pathology diagnoses, including second opinions, made exclusively by one of our 7 fellowship-trained gastrointestinal and liver pathologists. As a group, we are available to answer your questions and concerns about diagnoses at all times.

Experience

The gastrointestinal pathologists at Northwell Health are surgical pathologists who provide real-time consultations on challenging case materials. The service conducts routine intra-service quality review and maintains routine contact with clinical teams.

Expertise

Rebecca Meera Thomas, MBBS

  • Professor, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
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James Crawford, MD

  • Senior Vice President and Executive Director, Laboratory Services,
    Northwell Health
  • Professor and Chair, Pathology and Laboratory Medicine,
    North Shore University Hospital, Long Island Jewish Medical Center, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
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Cathy Qiuxi Fan, MD, MBBS

  • Assistant Professor, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
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Lili Lee, MD

  • Assistant Professor, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
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Lihui Qin, MD

Arvind Rishi, MBBS

  • Assistant Professor, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
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Margaret Yun Cho, MD

Timely results

The diagnostic reports for endoscopic and needle biopsies are routinely completed in 24-48 hours.

Tests

Histopathology

Surgical resections, endoscopic and laparoscopic biopsies and needle core biopsies for diseases including: gastroesophageal reflux, Barrett’s esophagus, gastritis, stomach cancer, enteritis, colorectal polyps and cancer, inflammatory bowel disease, chronic hepatitis, cirrhosis, hepatocellular carcinoma, pancreatitis and cancer, and biliary tract disease.

  • Endoscopic gastrointestinal biopsies
  • Liver biopsies
  • Gastrointestinal, pancreatic, hepatobiliary tumor evaluation
  • Surgical biopsies and resections

Cytology

  • Brushings and washings
  • Fine needle aspirations
  • Liquid-based technology with cell blocks, allowing the performance of special stains, immunohistochemistry, and molecular studies

Special Stains

  • Warthin Starry stain for Helicobacter pylori
  • Complete liver panel (trichrome, reticulin, iron, PAS with diastase)
  • Others (calcium, bile, mucins, copper, Congo Red, GMS, AFB, PAS/Alcian blue, etc.)

Immunohistochemistry and Flow Cytometry

Complete panels, including:

  • DNA mismatch repair proteins for colorectal carcinoma (MLH1, MSH2, MSH6, PMS2)
  • Therapeutic marker for colorectal carcinoma (EGFR, including in situ hybridization)
  • Gastrointestinal stromal tumor (CKIT, DOG1)
  • Organ-specific diagnostic markers (HEPPAR, CK7, CK20, CDX2, etc)
  • Prognostic markers (Ki-67, p53, etc.)
  • Complete lymphoma work-up including flow cytometry
  • Infectious agents (H. pylori, HSV, CMV, Adenovirus, EBV in situ hybridization)
  • DNA mismatch repair proteins for colorectal carcinoma (MLH1, MSH2, MSH6, PMS2)
  • Therapeutic marker for colorectal carcinoma (EGFR, including in situ hybridization)
  • Gastrointestinal stromal tumor profile
  • Organ-specific diagnostic markers
  • Prognostic markers (Ki-67, p53, etc.)
  • Complete lymphoma work-up including flow cytometry
  • Infectious agents (H. pylori, HBsAg, HBcAg, HSV, CMV, adenovirus, EBV in situ hybridization)

Molecular and Cytogenetic Testing

  • Solid tumor panels (31 gene panel for all Stage 4 adenocarcinomas)
  • C-KIT mutations
  • Lymphoma workup
  • Ploidy studies
  • Southern blot, PCR, and FISH techniques for:
  • Screening for microsatellite instability in colorectal cancer
  • Typing of lymphoma
  • Ploidy studies
  • Irinotecan sensitivity (UGTIAI) [separate brochure available for specimen handling]

(800) 472-5757

Find a location

Northwell Health Labs offers comprehensive laboratory services 24 hours a day, 7 days a week.

Fax: (516) 719-1037

 

Pathology & laboratory services

Our expert diagnostic and therapeutic services support Northwell Health physicians in diagnosing and monitoring disease.