Dubin-Johnson syndrome is a very rare genetic disorder in which a person has mild jaundice (yellowing of the skin and eyes) throughout their lifetime. This disorder, which is passed down through families, disturbs the body’s ability to remove bilirubin (a chemical produced by the liver) from the liver.
The bilirubin builds up in the liver, causing jaundice. Severly high levels of bilirubin can damage the brain and other organs.
Mild jaundice is the only symptom of Dubin-Johnson syndrome.