Primary Central Nervous System (CNS) Lymphoma

Primary Central Nervous System (CNS) Lymphoma

Lymphoma is a type of cancer that begins in the cells of the lymphatic system. This type of cancer in the brain is called primary central nervous system lymphoma (PCNSL). PCNSL is typically found in severely immunocompromised individuals. It is associated with the Epstein-Barr virus and is a primary brain tumor.

Lymphoma most often develops in the cerebral hemispheres but may also involve the eyes, the spinal cord or the cerebrospinal fluid. It is not unusual for this type of tumor to spread throughout the central nervous system. Some people may also have evidence of lymphoma elsewhere in the body.

Primary Central Nervous System Lymphoma Symptoms

PCNSL symptoms are the same as those associated with other types of brain tumors and depend on the area of the brain that is affected. Often there are tumors in different parts of the brain (multifocal). Some symptoms of PCNSL include:

  • Confusion
  • Headache
  • Memory loss
  • Nausea
  • Seizures (although uncommon)
  • Trouble speaking
  • Vision problems
  • Vomiting
  • Weakness or paralysis of muscles

Getting Diagnosed

Our team of specialists provides the most up-to-date evaluations using the latest diagnostic and imaging technology.

We work very closely with the departments of Neurosurgery, Interventional Neuroradiology, Neurology and Radiation Oncology, as well as the Normal Pressure Hydrocephalus Center and Skull Base Center to ensure an accurate diagnosis and the appropriate treatment for the best outcome.


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The Neuroscience Institute

We are dedicated to the world-class diagnosis and treatment of neurological diseases and disorders.