Pallister-Hall Syndrome is a very rare condition caused by Hypothalamic Hamartoma (HH), a malformation in the brain. It is usually diagnosed at birth.
This syndrome is characterized by extra fingers and/or toes, or the fusion of fingers or toes. In its most extreme form, the baby with Pallister-Hall Syndrome may have decreased function of the pituitary glands and/or blockage of the anus.
Infants with pituitary problems are immediately treated with hormone replacement. Surgery is used to remove the extra fingers or toes, or to correct the digestive system. If the child also experiences seizures (not as common as in other results of HH), he or she is given anti-convulsion medicines.