David Bernstein, MD, chief of the division of hepatology at North Shore University Hospital, is presenting a study he contributed to involving a new treatment for chronic hepatitis C today at the 45th annual Digestive Disease Week (DDW) meeting in Chicago, the North Shore-LIJ Health System announced today.
Hepatitis C is a contagious liver disease that, in its chronic form, can lead to cirrhosis (scarring) of the liver and liver cancer. It is the most common chronic viral infection in the United States.
The study involved more than 400 subjects with genotype 1A – a subgroup of the disease –who did not have cirrhosis.
“The majority of patients with hepatitis C in the United States are genotype 1A,” said Dr. Bernstein.
“Historically, this has been one of the most difficult patient population's to treat and cure.”
Subjects were given experimental drugs called ABT-450/Ombitasvir and Dasabuvir with and without the antiviral drug ribavirin for 12 weeks;
Researchers reported that the experimental drugs cured 97 percent of the subjects. The study appears in the May 4 online edition of the New England Journal of Medicine.
“This is an exciting advance in the treatment of chronic hepatitis C,” said Dr. Bernstein.
About North Shore-LIJ Health System
One of the nation's largest health systems, North Shore-LIJ delivers world-class clinical care throughout the New York metropolitan area, pioneering research at The Feinstein Institute for Medical Research, a visionary approach to medical education highlighted by the Hofstra North Shore-LIJ School of Medicine, and healthcare coverage to individuals, families and businesses through the North Shore-LIJ CareConnect Insurance Co. Inc. North Shore-LIJ cares for people at every stage of life at 17 hospitals and more than 400 outpatient physician practices throughout the region. North Shore-LIJ’s owned hospitals and long-term care facilities house more than 6,000 beds, employ more than 10,000 nurses and have affiliations with over 9,400 physicians. With a workforce of about 48,000, North Shore-LIJ is the largest private employer in New York State. For more information, go to www.northshorelij.com.