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David Langer, MD, wearing a grey tie
Chair, Department of Neurosurgery
Lenox Hill Hospital

Vice President, Neurosurgery, Western Region
Northwell Health

Professor, Neurosurgery and Radiology
Donald and Barbara Zucker School of Medicine at Hofstra/Northwell

David Langer, MD, is the chair of neurosurgery at Lenox Hill Hospital and Vice President of neurosurgery for Northwell Health's Western Region. He is Professor of Neurosurgery and Radiology at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell. Internationally recognized as an expert in cerebral revascularization and cerebral aneurysms, his work focuses on diseases of the brain vessels. Dr. Langer's work has been featured in numerous peer-reviewed publications and he has spoken nationally and internationally on vascular disorders such as aneurysms and arteriovenous malformations (AVMs) of the brain. He is one of the few cerebral bypass surgeons in the country.

A third generation physician, Dr. Langer attended the University of Pennsylvania for undergraduate and medical school. He stayed on at Penn and completed his neurosurgical residency under the direction of Eugene Flamm, MD. He later joined Dr. Flamm at a new neurosurgical institute in New York City in 1998. Dr. Langer also completed a mid-career fellowship at the University at Buffalo in cerebrovascular disease treatment including aneurysms, AVMs, and carotid disease.

Dr. Langer worked at the Continuum Health System at Mount Sinai in New York until 2010, when he joined the neurosurgery department at Northwell Health. Dr. Langer established the Moyamoya Center of Neuroscience Institute and developed a project focused on the use of social networking technology and video to enhance the patient experience and improve the medical record which has become Playback Health – a Snapchat and Instagram for healthcare. This project has grown into the health system, supported Cirrus Health, which continues to creatively disrupt the status quo in patient communication and the current electronic medical record.

In 2013 Dr. Langer was recruited as director of neurosurgery at Lenox Hill and subsequently went on to help establish the first Department of Neurosurgery at Lenox Hill Hospital. He is currently Chairman of this new department. His goal is to further expand this program by creating an environment emphasizing collaboration, communication and world-class clinical care. He is currently involved in the study, development and adoption of the use of 3 dimensional exoscopic surgery in spine and cranial surgery. 

Dr. Langer has been recognized as a Top Doctor and Best Doctor by numerous publications. He is currently a peer reviewer for the journals Neurosurgery and American Association of Neurological Surgeons' Neurosurgeon. He is on the medical advisory boards of Box Inc. and Cisco Systems. He is also a founding member of the board of the Brain Technology Institute and an active member of the American Association of Neurological Surgeons and the Congress of Neurological Surgeons, as well as the cerebrovascular subsection of these organizations. In addition, Dr. Langer serves on the editorial board for Operative Neurosurgery’s digital platforms in the journal’s Surgical Video section. In 2015, Dr. Langer received North Shore-LIJ Health System's President's Award. In 2018, Dr. Langer recieved The Sally Harrington Goldwater Memorial Visiting Professor Award from the Barrow Neurological Foundation. 

He has appeared on CNN, FOX, ABC, and CBS as well as the Dr. Oz Show. He has also frequently quoted in The New York Times and numerous other print news sources. In November 2015, Dr. Langer was featured in The Wall Street Journal article "What Patients Need to Remember After Leaving the Hospital" for his innovative technology to record crucial steps of patient's experience in the hospital.


"Castle Connolly Top Doctor 2018, David J. Langer MD"
Identified as a Top Doctor by Castle Connolly

Dr. Langer was selected by Castle Connolly as a Top Doctor, nominated by his peers for being among the best in his field. Physicians chosen by Castle Connolly are regarded as the most outstanding healthcare providers throughout the region and nationally.


We know neurosurgery is a complex field, and patients often struggle to recall details of their appointments, including follow-up instructions. Northwell and Playback Health have a solution.

Learn more

Clinical Interests

  • Spinal Diseases
  • Moyamoya Disease
  • Neurovascular Disease
  • Cerebral Bypass
  • Brain Aneurysms
  • Carotid Disease
  • Complex and Minimally Invasive Spine Surgery
  • Acoustic Neuromas
  • Benign Brain Tumors

Research Interests

  • Medical Informatics
  • Cerebral Revascularization

Professional Societies

  • American Academy of Neurological Surgeons
  • Congress of Neurological Surgeons
  • Cerebrovascular Section, American Academy of Neurological Surgeons/Congress of Neurological Surgeons
  • Advisory Board Member, Box, Inc.
  • Advisory Board Member, Cisco Systems
  • Editorial Board, Operative Neurosurgery

Awards and Professional Recognition

  • The Sally Harrington Goldwater Memorial Visiting Professor Award from the Barrow Neurological Foundation, 2018
  • President’s Award, North Shore-LIJ Health System, 2015
  • Upjohn Cerebrovascular Resident Research Award, American Academy of Neurological Surgeons, 1995 
  • Morris Ginsberg Memorial Prize, 1991
  • I.S. Ravdin Memorial Prize, 1991
  • George Householder Memorial Award, 1991
  • Four Schools Physician Scientist Award, 1989
The latest news for David Langer, MD
Playback Health and David Langer, MD, are featured in this HealthLeaders Magazine story.
HealthLeaders covers David Langer's mobile app Playback Health, which allows users to review their doctor's visits.
Lenox Hill Hospital neurosurgeons cite better optics, ergonomics, maneuverability and reduced surgeon fatigue when using an HD3D video exoscope while performing spinal surgeries.

Abstracts and Presentations

Langer, DJ: Operative Visualization- The Next Generation, Mount Sinai Digital Neuro Symposium, New York, NY. December 7, 2018.

Langer, DJ: Operating microscope in Neurosurgery, University of Kansas Health System, Invited Lecturer, Kansas City, MO. November 2018.

Langer, DJ: CNS Annual Meeting, Presentation on the Orbeye Exoscope, Houston, TX. October 2018.

Langer, DJ: Management of Spinal AVM, CNS Annual Meeting, Houston, TX. October 2018.

Langer, DJ: 5th Annual EANS Vascular Section Meeting, Nice, France. September 2018.

Langer, DJ: Moderator Bypass for Ischemia. Moderator Parent and Branch Vessel Occlusion during Aneurysm Surgery. Panel Discussant Intraoperative Complication Management. Cerebrovascular and Skull Base Symposium at Brigham Womens Hospital, Boston, MA. September 2018.

Langer, DJ: Next Generation of Operative Innovation, Hatzolah of Williamsburg, Invited Lecturer, Brooklyn, NY. July 2018.

Langer, DJ: The Olympus Orbeye and the Future of the Operating Microscope, Northwell Neuroscience Institute Annual Symposium, Manhasset, NY. June 2018.

Langer, DJ: Lenox Hill Neurosurgery III Lessons of Success and Failure in Neurovascular Treatment. Course Director. Lenox Hill Hospital, New York, NY. June 1, 2018.

Langer, DJ: Cerebral Bypass and the Next Generation, Israeli Neurovascular Conference, Tel Aviv, Israel. May 2018.

Langer, DJ: Leadership in Neurosurgery, Leadership in Healthcare Course, Rosemont, IL. May 2018.

Langer, DJ: Future of Cerebral Revascularization, Grand Rounds, Barrow Neurological Institute, Phoenix, AZ. May 2018.

Langer, DJ: Cerebral Revascularization for Skull Base Tumors: How I do it, The Lenox Hill Skull Base Course, Lenox Hill Hospital, New York, NY. March 15, 2018.

Langer, DJ: Operating exoscope in Neurosurgery, Jackson Hole, WY. March 2018.

Langer, DJ: LINNC Seminar- US Edition, Moderator AVM and Aneurysm Session, Neurosurgery at Jackson Hole, New York, NY. March 2018.

Langer, DJ: 2nd Annual Winter Neurosurgical Forum, Operating exoscope in Neurosurgery, Steamboat Springs, CO. February 2018.

Langer, DJ: Use of internal maxillary artery for bypass, North American Skull Base Annual Conference, Coronado, CA. February 2018

Langer, DJ: Vascular Neurosurgery and patient satisfaction, National Undergraduate and Foundation Surgery Conference, London, UK. January 2018.

2017 CNS Leadership in Healthcare Course, Chicago, IL

2017 University of Arizona Neuroscience Grand Rounds- Bypass surgery after Pipeline and COSS”, Tucson, AZ

2017 Montreal Neurological Institue Grand Rounds- “Bypass surgery after COSS and Flow, Diversion”, Montreal, CA

2017 AANS/CNS Joint Cerebrovascular Section Annual Meeting- Complex open vascular surgery cases”, Houston, TX

2017 Inaugural Winter Neurosurgical Forum- Bypass surgery after COSS and Pipeline”, Steamboat Springs, CO

2016 AVM World Congress- Bypass surgery after COSS and Pipeline, Napa, CA

2016 CAN Annual Meeting- Leadership Development for the practicing Neurosurgeon, San Diego, CA

2016 EANS/ESMINT- Treatment of fusiform VB Aneurysms, Nice, France

2016 AANS Annual Meeting- Innovation in open vascular Neurosurgery, Chicago, IL

2016 Tel Aviv Medical Center Department of Neurosurgery Grand Rounds- "Moyamoya Disease Diagnosis and Treatment"

2015 CNS Annual Meeting- “Leaders are not Born, They are Made: Executive Leadership Training for the Medical Professional”, New Orleans, LA

2015 Philadelphia PA University of Pennsylvania School of Medicine, Penn HealthX Seminar, Digital Healthcare- letting the cloud drive clinical UX”

2015 Austral Asian Congress of Neurological Surgeons- IMAX and IT- New Horizons in Neurosurgery

2015 Lenox Hill Auxiliary Symposium “Breakthroughs in Technology: revolutionizing patient care”

2014 University Medical Center Utrecht, “IMAX Bypass Indications and Treatment”, Utrecht, Holland

2014 University of Texas Houston Neurosurgery Grand Rounds, “Internal Maxillary Bypass new technique for EC-IC bypass”, Houston, TX

2014 Box-works 2014 The Innovation Curve in Healthcare, “New Technologies and Policy Implications”, San Francisco CA

2013 International Perspectives in Neurovascular Disease, “Past, Present and Future in Neurovascular Disease”, Bern, Switzerland

2013 Bern European Revascularization Course , “In Situ Bypass”, Bern, Switzerland

2012 CNS Vascular Section, “Cerebrovascular Neurosurgery - Are we leading the way or losing our way?”, New Orleans, LA

 2012 CNS Vascular Section, "Final Results of ELANA IDE Study on High Flow Cerebral Bypasses: Anterior Circulation Aneurysms”, New Orleans, LA

2012 AANS/CNS Neurovascular Meeting Bypass Surgery, “The Red- Headed Step Child”, New Orleans, LA

2012 AANS/CNS Neurovascular Meeting, "Preliminary Results of the ELANA IDE Study on High Flow Cerebral Bypasses - Anterior Circulation Aneurysms”, New Orleans, LA

2012 University of Illinois Chicago Grand Rounds and Visiting Professor, “New Technology in Healthcare Communication” , Chicago, ILL

2012 World Congress on Cerebral Revascularization, “Side to side bypass”, St. Louis, MO 2011

University of Cincinnati Grand Rounds and Visiting Professor, “The ELANA technique”, Cincinnati, OH

2011 Allegheny General Hospital “Microscopic and Endoscopic Approaches to the Skull Base”, Pittsburgh, PA

2011 University of Bern, “Revascularization Course”, Bern, SU 2011 CNS "ELANA- Indications and Outcomes", Washington, DC

2011 2nd Florida Aneurysm Workshop,“ In situ bypass techniques”, Miami, FL

2010 MCG Technology Fair “Medical records for the iPhone generation”, Augusta, GA 2009 Sidney Hollin Memorial Lecture Mt. Sinai School of Medicine, New York, NY 2009  

Course Director, 2009 Neurosymposium, New York City, NY

2009 SUNY Buffalo Neurosurgery Grand Rounds, "The Future of Neurovascular Surgery", Buffalo, NY

2009 3C Conference Jackson Hole, "New Technologies in Neurovascular Surgery", Jackson, WY

2008 CNS "New Technologies in Neurovascular Surgery", Orlando, FL

2008 Young Vascular Neurosurgeons Conference, “ The ELANA technique”, Sarasota FL 2007

St Louis University World Congress on Cerebral Revascularization,“ Use of Quantititative MRA (NOVA) in cerebral revascularization”, St Louis, MO 2007

Downstate University Neurosurgical Grand Rounds, "Future Technologies in

Cerebrovascular Bypass Surgery", Brooklyn, NY

2007 Johns Hopkins University Neurosurgical Grand Rounds, "Future Technologies in Cerebrovascular Bypass Surgery", Baltimore, MD

2007 Columbia University Neurosurgical Grand Rounds, "Future Technologies in Cerebrovascular Bypass Surgery", New York, NY

2007 Allegheny Hospital Neurosurgical Grand Rounds, "Future Technologies in Cerebrovascular Bypass Surgery", Pittsburgh, PA

2006 St Louis University Cerebral Revascularization Meeting, Course Co-Director, St. Louis, MO

2006 Neurosurgery Grand Rounds University of Texas, "New Avenues in High Flow EC-IC Bypass", Dallas, TX

2003 Neurosurgery Grand Rounds University of Illinois/Chicago "New Avenues In High Flow EC-IC Bypass", Chicago, IL

2002-2005 St Louis University Cerebral Revascularization Faculty "New Avenues in High Flow EC-IC Bypass", St. Louis, MO

2002-2005 Academy of Neurology “The Neurologist’s Role in a Multidisciplinary Approach to Cerebral Aneurysms, Pial and Dural AVMs”

2002 AANS/CNS Vascular Section Meeting, “Management of Residual Anterior Communicating Artery Aneurysms in Patients with Subarachnoid Hemorrhage”, Dallas, TX

1999 Neurosurgery Grand Rounds Tufts University School of Medicine “Controversies in the Management of Cerebral Arterial Aneurysms”, Boston, MA

1999 International Society of Neurological Emergencies, “Clinical evaluation and management of acute hydrocephalus”, “Intensive care management of cerebral vasospasm”, Venice, Italy

1996 Sedona Spring Brain Conference Plenary speaker, “Bypassing the Nucleus, mRNA as Gene Therapy”, Sedona, AZ

Publications

Ellis JA, Sudhakar TD, Rahman A, Ortiz RA, Langer DJ, Boockvar JA, Mandel S. Glomus tumors of the head and neck. Practical Neurology. In Press 2018.

Nossek E, Schneider JR, Kwan K, Kulason KO, Du V, Chakraborty S, Rahme R, Faltings L, Ellis J, Ortiz R, Boockvar JA, Langer DJ.: Technical Aspects and Operative Nuances Using a High-Definition 3-Dimensional Exoscope for Cerebral Bypass Surgery. Operative Neurosurgery (Hagerstown). December 3, 2018.

Rahme R, Sudhakar T, Alimi M, White T, Ortiz R, Langer D.: Cerebral Hyperperfusion Syndrome by the Numbers: Transient Focal Neurological Deficit, Imaging-Proven Focal Hyperperfusion, and High Graft Flow Rate Following Superficial Temporal Artery-Middle Cerebral Artery bypass in a Patient With Symptomatic Carotid OcclusionCase Report. Operative Neurosurgery. December 1, 2018. 0:1-6.

Schneider JR, Shatzkes DR, Scharf SC, Tham TM, Kulason KO, Buteau FA, Del Prete M, Chakraborty S, Anderson TA, Asiry S, Beauregard JM, Langer DJ, Costantino PD, Boockvar JA.: Neuroradiological and Neuropathological Changes After 177Lu-Octreotate Peptide Receptor Radionuclide Therapy of Refractory Esthesioneuroblastoma. Operative Neurosurgery (Hagerstown). Dec 1, 2018.

Khalessi AA, Rahme R, Rennert RC, Borgas P, Steinberg JA, White TG, Santiago-Dieppa DR, Boockvar JA, Hatefi D, Pannell JS, Levy M, Langer DJ.: First-in-Man Clinical Experience Using a High-Definition 3-Dimensional Exoscope System for Microneurosurgery. Operative Neurosurgery (Hagerstown). November 26, 2018.

Ellis JA, Nossek E, Kronenburg A, Langer DJ, Ortiz RA.: Intracranial Aneurysm: Diagnostic Monitoring, Current Interventional Practices, and Advances. Current Treatment Options in Cardiovascular Medicine. October 24, 2018. 20(12):94.

Schneider JR, Kulason KO, Khan MB, White TG, Kwan K, Faltings L, Kobets AJ, Chakraborty S, Ellis JA, Ortiz RA, Filippi CG, Langer DJ, Boockvar JA.: Commentary: Advances in Glioblastoma Therapies: A Collaborative Effort Between Physicians and the Biotechnology Industry. Neurosurgery. October 1, 2018. 83(4):E162-E168.

Shakir HJ, Shakir MA, Sharan AD, Chambless LB, Langer DJ, Davies JM, Levy EI. : Commentary: The Future Currency of Neurosurgery is Data. Neurosurgery. Sep 1, 2018.

Kwan K, Schneider JR, Du V, Falting L, Boockvar JA, Oren J, Levine M, Langer DJ: Lessons Learned Using a High-Definition 3-Dimensional Exoscope for Spinal Surgery. Operative Neurosurgery (Hagerstown). August 14, 2018.

Nossek E, Langer DJ: Internal Maxillary Artery to Middle Cerebral Artery Cranial Bypass: The New "Work Horse" for Cerebral Flow Replacement. World Neurosurgery. July 2018.

Schneider JR, Kulason KO, Khan MB, White TG, Kwan K, Faltings L, Kobets AJ, Chakraborty S, Ellis JA, Ortiz RA, Filippi CG, Langer DJ, Boockvar JA.: Commentary: Advances in Glioblastoma Therapies: A Collaborative Effort Between Physicians and the Biotechnology Industry. Neurosurgery. Jun 8, 2018.

Kulason KO, Schneider JR, Chakraborty S, Filippi CG, Pramanik B, Wong T, Fralin S, Tan K, Ray A, Alter RA, Ortiz R, Demopoulos A, Langer DJ, Boockvar JA.: Superselective intraarterial cerebral infusion of cetuximab with blood brain barrier disruption combined with Stupp Protocol for newly diagnosed glioblastoma. Journal of Experimental Therapeutics and Oncology. May 2018. 12(3):223-229.

Ellis JA, Nossek E, Kronenburg A, Langer DJ, Ortiz RA.: Intracranial Aneurysm: Diagnostic Monitoring, Current Interventional Practices, and Advances. Current Treatment Options in Cardiovascular Medicine. October 24, 2018. 20(12):94.

Schneider JR, Kulason KO, Khan MB, White TG, Kwan K, Faltings L, Kobets AJ, Chakraborty S, Ellis JA, Ortiz RA, Filippi CG, Langer DJ, Boockvar JA.: Commentary: Advances in Glioblastoma Therapies: A Collaborative Effort Between Physicians and the Biotechnology Industry. Neurosurgery. October 1, 2018. 83(4):E162-E168.

Shakir HJ, Shakir MA, Sharan AD, Chambless LB, Langer DJ, Davies JM, Levy EI. : Commentary: The Future Currency of Neurosurgery is Data. Neurosurgery. Sep 1, 2018.

Kwan K, Schneider JR, Du V, Falting L, Boockvar JA, Oren J, Levine M, Langer DJ: Lessons Learned Using a High-Definition 3-Dimensional Exoscope for Spinal Surgery. Operative Neurosurgery (Hagerstown). August 14, 2018.

Nossek E, Langer DJ: Internal Maxillary Artery to Middle Cerebral Artery Cranial Bypass: The New "Work Horse" for Cerebral Flow Replacement. World Neurosurgery. July 2018.

Schneider JR, Kulason KO, Khan MB, White TG, Kwan K, Faltings L, Kobets AJ, Chakraborty S, Ellis JA, Ortiz RA, Filippi CG, Langer DJ, Boockvar JA.: Commentary: Advances in Glioblastoma Therapies: A Collaborative Effort Between Physicians and the Biotechnology Industry. Neurosurgery. Jun 8, 2018.

Kulason KO, Schneider JR, Chakraborty S, Filippi CG, Pramanik B, Wong T, Fralin S, Tan K, Ray A, Alter RA, Ortiz R, Demopoulos A, Langer DJ, Boockvar JA.: Superselective intraarterial cerebral infusion of cetuximab with blood brain barrier disruption combined with Stupp Protocol for newly diagnosed glioblastoma. Journal of Experimental Therapeutics and Oncology. May 2018. 12(3):223-229.

Kulason KO, Schneider JR, Rahme R, Ratzon F, Anderson TA, Shatzkes DR, Filippi CG, Costantino PD, Langer DJ, Boockvar JA: Suprasellar and third ventricular cavernous malformation: Lessons learned in differential diagnosis and surgical planning. Surgical Neurology International. 2017 Oct 13

Bonda DJ, Labib M, Katz JM, Ortiz RA, Chalif D, Setton A, Langer DJ, Dehdashti AR.: Intracranial Bypass of Posterior Inferior Cerebellar Artery Aneurysms: Indications, Technical Aspects, and Clinical Outcomes. Operative Neurosurgery (Hagerstown). 2017 Oct 1

Fanous AA, White TG, Hirsch MB, Chakraborty S, Costantino PD, Langer DJ, Boockvar JA.: Frameless and Maskless Stereotactic Navigation with a Skull-Mounted Tracker. Neurosurgery. 2017 Jun

White T, Chakraborty S, Lall R, Fanous AA, Boockvar J, Langer DJ.: Frameless Stereotactic Insertion of Viewsite Brain Access System with Microscope-Mounted Tracking Device for Resection of Deep Brain Lesions: Technical Report. Cureus. 2017 Feb 4

Alobaid A, Nossek E, Wagner K, Setton A, Dehdashti AR, Langer D, Chalif D.: Paradigms for single-patient multimodality treatment for cerebral aneurysms: single-center eleven-year experience. Neurosurgery Review. 2017 Jan 14

Alobaid A, Nossek E, Wagner K, Setton A, Dehdashti AR, Langer D, Chalif D.: Paradigms for single-patient multimodality treatment for cerebral aneurysms: single-center eleven-year experience. Neurosurg Rev. 2017 Jan 14. doi: 10.1007/s10143-016-0810-z.

Tham T, White TG, Chakraborty S, Lall RR, Ortiz R, Langer DJ, Shatzkes D, Filippi CG, Kraus D, Boockvar JA, Costantino PD: Intra-arterial cetuximab for the treatment of recurrent unresectable head and neck squamous cell carcinoma<sup></sup>;J Exp Ther Oncol. 2016 Nov

Chakraborty S, Filippi CG, Burkhardt JK, Fralin S, Ray A, Wong T, Ortiz R, Langer DJ, Boockvar JA: Durability of single dose intra-arterial bevacizumab after blood/brain barrier disruption for recurrent glioblastoma: J Exp Ther Oncol. 2016 Nov;11(4):261-267.

Chakraborty S, Filippi CG, Wong T, Ray A, Fralin S, Tsiouris AJ, Praminick B, Demopoulos A, McCrea HJ, Bodhinayake I, Ortiz R, Langer DJ, Boockvar JA: Erratum to: Superselective intraarterial cerebral infusion of cetuximab after osmotic blood/brain barrier disruption for recurrent malignant glioma: phase I study: J Neurooncol. 2016 Jul

White TG, O'Donnell D, Rosenthal J, Cohen M, Aygok G, Nossek E, Langer DJ: Trends in Cerebral Revascularization in the Era of Pipeline and COSS, World Neurosurg. 2016 Apr 9

Chakraborty S, Filippi CG, Wong T, Ray A, Fralin S, Tsiouris AJ, Praminick B, Demopoulos A, McCrae H, Bodhinayake I, Ortiz R, Langer DJ, Boockvar JA: Superselective intraarterial cerebral infusion of cetuximab after osmotic blood/brain barrier disruption for recurrent malignant glioma: phase I study, J Neurooncol. 2016 Mar 5

Chakraborty S, Bodhinayake I, Chiluwal A, Langer DJ, Ruggieri R, Symons M, Boockvar JA: Neuro-oncology biotech industry progress report, J Neurooncol. 2016 Feb 20

Nossek E, Setton A, Karimi R, Dehdashti A, Langer D, Chalif D: Analysis of superiorly projecting anterior communicating artery aneurysms: anatomy, techniques and outcome. A proposed classification system Neurosurgical Review 12/2015;DOI:10.1007/s101143-015-0677-4.2.18

Nossek, E., Costantino, P.D., Chalif, D.J., Ortiz, R.O., Dehdashti, A.R., Langer, D.J., Forearm Cephalic Vein Graft for Short , “Middle” Flow, Internal Maxillary Artery to Middle Cerebral Artery Bypass, Operative Neurosurgery, Accepted for publication 2015

Nossek E, Langer DJ: How I Do It: Combined direct (STA-MCA) and indirect (EDAS) EC-IC bypass, Acta Neurosurgica 156(11):2079-2084, 2014

Nossek E, Costantino P, Dehdashti A, Chalif D, Setton A, Eisenberg M, et al: Internal maxillary artery to middle cerebral artery bypass: Infratemporal approach for subcranial- intracranial (SC-IC) Bypass. Neurosurgery 75(1):87-95, 2014

Tandon A, Chandela S, Langer D, Sen C: A novel sling technique for microvascular decompression of a rare anomalous vertebral artery causing cervical radiculopathy. Neurosurg Focus 35(3):E2, 2013

Rodríguez-Hernández A, Josephson SA, Langer D, Lawton MT: Bypass for the prevention of ischemic stroke. World Neurosurg 76(6 Suppl):S72-9 Review, 2011 Erratum in: World Neurosurg. 78(6):e1, 2012

Kan P, Yashar P, Langer DJ, Siddiqui AH, Levy EI: Posterior inferior cerebellar artery to posterior inferior cerebellar artery in situ bypass for the treatment of Bow hunter's-type dynamic ischemia in holovertebral dissection. World Neurosurg 78(5):553.e15-7, 2012

Wolfe SQ, Manzano G, Langer DJ, Morcos JJ: Cavernous malformation of the oculomotor nerve mimicking a partially thrombosed posterior communicating artery aneurysm: Report of two cases. Neurosurgery 69(2:E470-4, 2011

Chandela S, Chakraborty S, Ghobrial GM, Jeddis A, Sen C, Langer DJ: Contralateral mini craniotomy for clipping of bilateral ophthalmic artery aneurysms using unilateral proximal carotid control and sugita head frame. World Neurosurg 75(1):78-82, 2011

Korja M, Sen C, Langer D: Operative nuances of side-to-side in situ posterior inferior cerebellar artery-posterior inferior cerebellar artery bypass procedure. Neurosurgery 69(2):E470-4, 2010

Hauck EF, Natarajan SK, Langer DJ, Hopkins LN, Siddiqui AH, Levy EI: Retrograde trans posterior communicating artery snare-assisted rescue of lost access to a foreshortened pipeline embolization device: complication management. Neurosurgery 67(2 Suppl Operative):495-502, 2010

Levy EI, Siddiqui AH, Hopkins LN, Langer DJ, Ogilvy CS: Cerebrovascular surgery: Evolution or obsolescence, J Neurosurg 111(1):195-7, 2009

Starke RM, Chwajol M, Lefton D, Sen C, Berenstein A, Langer DJ: Occipital artery-to- posterior inferior cerebellar artery bypass for treatment of bilateral vertebral artery occlusion: the role of quantitative magnetic resonance angiography noninvasive optimal vessel analysis: Technical case report. Neurosurgery 64(4):E779-81, 2009

Van Doormaal TP, Van der Zwan A, Verweij BH, Han KS, Langer DJ, Tulleken CA: Treatment of giant middle cerebral artery aneurysms with a flow replacement bypass using the excimer laser- assisted nonocclusive anastomosis technique. Neurosurgery 63(1):12-20, 2008

van Doormaal TP, van der Zwan A, Verweij BH, Langer DJ, Tulleken CA: Treatment of giant and large internal carotid artery aneurysms with a high-flow replacement bypass using the excimer laser-assisted nonocclusive anastomosis technique. Neurosurgery 62(6 Suppl 3):1411-18, 2008

Langer DJ, Van Der Zwan A, Vajkoczy P, Kivipelto L, Van Doormaal TP, Tulleken CA: Excimer laser-assisted nonocclusive anastomosis. An emerging technology for use in the creation of intracranial-intracranial and extracranial-intracranial cerebral bypass. Neurosurg Focus 24(2):E6, 2008

Heran NS, Song JK, Kupersmith MJ, Niimi Y, Namba K, Langer DJ et al: Large ophthalmic segment aneurysms with anterior optic pathway compression: Assessment of anatomical and visual outcomes after endosaccular coil therapy. J Neurosurg 106(6):968-75, 2007

Berenstein, A, Song JK, Niimi Y, Namba K, Heran NS, Brisman JL, et al: Treatment of cerebral aneurysms with hydrogel-coated platinum coils (hydrocoil): Early single-center experience. American Journal of Neuroradiology 27:1834-1840, 2006

Van Doormaal TP, Van der Zwan A, Verweij BH, Langer DJ, Tulleken CA: Treatment of giant and large internal carotid artery aneurysms with a high-flow replacement bypass using the excimer laser-assisted nonocclusive anastomosis technique. Neurosurgery 59(4 Suppl 2), 2006

Szelényi A, Langer D, Kothbauer K, De Camargo AB, Flamm ES, Deletis V: Monitoring of motor evoked potentials monitoring during cerebral aneurysm surgery: intraoperative changes and postoperative outcome, J Neurosurgery Vol 105:5, 2006

Langer DJ, Lefton DR, Ostergren L, Brockington CD, Song J, Niimi Y, et al: Hemispheric revascularization in the setting of carotid occlusion and subclavian steal: A diagnostic and management role for quantitative magnetic resonance angiography? Neurosurgery 58(3):528-33; discussion 528-33, 2006

Langer DJ, Song JK, Niimi Y, Chwajol M, Lefton DR, Brisman JL, Molofsky W,Kupersmith MJ, Berenstein A: Transarterial embolization of vein of Galen malformations: the use of magnetic resonance imaging noninvasive optimal vessel analysis to quantify shunt reduction. Report of two cases. J Neurosurg 104(1 Suppl):41-5, 2006

Langer DJ, Vajkoczy P: ELANA: Excimer Laser-Assisted Nonocclusive Anastomosis for extracranial-to-intracranial and intracranial-to-intracranial bypass: A review. Skull Base 15(3):191- 205, 2005

Szelényi A, Kothbauer K, de Camargo AB, Langer D, Flamm ES, Deletis V: Motor evoked potential monitoring during cerebral aneurysm surgery: technical aspects and comparison of transcranial and direct cortical stimulation. Neurosurgery 57(4 Suppl):331-8; discussion 331-8, 2005

Kupersmith MJ(1), Stiebel-Kalish H, Huna-Baron R, Setton A, Niimi Y, Langer D et al: Cavernous carotid aneurysms rarely cause subarachnoid hemorrhage or major neurologic morbidity. J Stroke Cerebrovasc Dis 11(1):9-14. 2002

Kariko K, Keller JM, Harris VA, Langer DJ, Welsh FA: In vivo protein expression from mrna delivered into adult rat brain. J. Neurosci Methods 105:77-86, 2001

Volpe NJ, Sharma MC, Galetta SL, Langer DJ, Liu GT, Hurst RW et al: Orbital drainage from cerebral arteriovenous malformations. Neurosurgery 46(4):820-4, 2000

Langer DJ, Lasner TM, Hurst RW, Flamm ES, Zager EL, King JT Jr: Hypertension, small size, and deep venous drainage are associated with risk of hemorrhagic presentation of cerebral arteriovenous malformations. Neurosurgery 42(3):481-6; discussion 487-9,1998

Kariko K, Kuo A, Barnathan ES, Langer DJ: Phosphate-enhanced transfection of cationic lipid- complexed mRNA and plasmid DNA. Biochim Biophys Acta 1369(2):320-34,1998

Neschis DG, Safford SD, Raghunath PN, Langer DJ, David ML, Hanna AK, et al: Thermal preconditioning before rat arterial balloon injury: limitation of injury and sustained reduction of intimal thickening. Arterioscler Thromb Vasc Biol 18(1):120-6, 1998

O'Connor WM, Davidson BL, Kaplitt MG, Abbey MV, During MJ, Leone P: Adenovirus vector-mediated gene transfer into human epileptogenic brain slices: Prospects for gene therapy in epilepsy. Exp Neurol 148(1):167-78, 1997

Freese A, Kaplitt MG, O'Connor WM, Abbey M, Langer D, Leone P et al: Direct gene transfer into human epileptogenic hippocampal tissue with an adeno-associated virus vector: Implications for a gene therapy approach to epilepsy. Epilepsia 38(7):759-66, 1997

Langer DJ, Kuo A, Kariko K, Ahuja M, Klugherz BD, Ivanics KM et al: Regulation of the endothelial cell urokinase-type plasminogen activator receptor. Evidence for cyclic AMP-dependent and protein kinase C-dependent pathways. Circ Res 72(2):330-40, 1993

Langer DJ, Kuo A, Kariko K, Cines B, Barnathan ES: Regulation of the urokinase receptor on human endothelial cells-evidence for camp dependent and independent pathways. Clinical Research 38:319A, 1990

Books, Book Chapters and Reviews

LLanger, David, Labib, Mohammed, Al-Shaar, Hussam Abou: Chapter 18. Arterial Bypass, in Veznedaroglu E (ed): Controversies in Vascular Neurosurgery. Switzerland: Springer 2016

Chakraborty S, Van Doormaal T, Kivipelto L, Langer D: Chapter 14. EC IC bypass using elana technique, in Abdulrauf SI (ed): Cerebral Revascularization: Techniques in Extracranial-to- Intracranial Bypass Surgery. St. Louis M: Elsevier Saunders, 2010, pp.145-153

Korja M, Kivipelto L, Sen C, Langer D: Chapter 10. The state of the art in cerebrovascular bypasses: Side to side in situ PICA-PICA Bypass, in Abdulrauf SI (ed): Cerebral Revascularization: Techniques in Extracranial-to-Intracranial Bypass Surgery. St. Louis M: Elsevier Saunders, 2010, pp.113-118

Schwartz LF, Langer DJ, LeRoux PD: Chapter 15, Clinical presentation of cerebral aneurysms and subarachnoid hemorrhage, In: LeRoux PD Winn HR Newell D (ed): Management of Cerebral Aneurysms. Philadelphia: W.B. Saunders, 2003

Langer DJ, Flamm ES: Surgical Treatment of Anterior Circulation Aneurysms, in Stein S (ed): Neurobase: CD ROM Textbook of Neurosurgery. Westminster MD: Arbor Publishing Company, 1999

Langer DJ, Zager E, Flamm ES: Parasurgical management of aneurysmal subarachnoid hemorrhage, in: Cruz, J. (ed): Neurologic and Neurosurgical Emergencies. Philadelphia: W.B. Saunders, 1998, p. 205-241

Sattelle DB, Langer DJ, Haniff CA, Ellar DJ: Laser light scattering determination of size and particle composition of delta endotoxin crystals from b. thuringiensis, in Royal Society of Chemistry (ed), Royal Society of Chemistry Dynamic Properties of Biomolecular Assemblies. London: Royal Society of Chemistry, 1989